Genetic influences on adolescent behavior
November 1, 2016
Dick DM, Adkins AE Kuo SI
Neurosci Biobehav Rev 2016 70:198-205. doi: 10.1016/j.neubiorev.2016.07.007. PMCID: PMC5074858
Ibudilast attenuates expression of behavioral sensitization to cocaine in male and female rats.
October 1, 2016
Poland RS, Hahn YK, Knapp PE, Beardsley PM, Bowers MS
2016 Neuropharmacology. 109:281-92. doi: 10.1016/j.neuropharm.2016.06.024. PMCID: PMC5404892.
Disentangling the Role of Astrocytes in Alcohol Use Disorder
September 1, 2016
Adermark L, Bowers MS
2016 Alcohol. Clin. Exp. Res. 40(9):1802-1816. doi: 10.1111/acer.13168. PMID: PMC5407469.
The genetics of addiction; Where do we go from here?
September 1, 2016
Dick DM
2016 J. Stud. Alcohol Drugs 77:673-675 doi: 10.15288/jsad.2016.77.673. PMID: 27588521
Predicting tobacco use across the first year of college.
July 1, 2016
Cooke ME, Nasim, A, Cho SB, Kendler, KS, Clark, SL, Dick DM
2016 Am. J. Health Behav. 40(4):484-495 doi: 10.5993/AJHB.40.4.10. PMCID: PMC4946338.
A prospective longitudinal model predicting early adult alcohol problems: evidence for a robust externalizing pathway.
April 1, 2016
Edwards AC, Gardner CO, Hickman M, Kendler KS
2016 Psychol Med. 46(5):957-68. doi:10.1017/S0033291715002457. PMCID: PMC4801516.
N-acetylcysteine decreased nicotine reward-like properties and withdrawal in mice.
March 1, 2016
Bowers MS, Jackson A, Maldoon PP, Damaj MI
2016 Psychopharmacology (Berl). 233(6):995-1003. doi: 10.1007/s00213-015-4179-4. PMCID: PMC4819399.
Identification of quantitative trait loci and candidate genes for an anxiolytic-like response to ethanol in BXD recombinant inbred strains
March 1, 2016
Putman AH, Wolen AR, Harenza JL, Yordanova RK, Webb BT, Chesler EJ, Miles MF.
2016 Genes Brain Behav. 15(4):367-81. doi: 10.1111/gbb.12289. PMCID: PMC4852167.
JEPEGMIX: gene-level joint analysis of functional SNPs in cosmopolitan cohorts.
January 15, 2016
Lee D, Williamson VS, Bigdeli TB, Riley BP, Webb BT, Fanous AH,Kendler KS, Vladimirov VI, Bacanu SA
2016 Bioinformatics 32(2):295-297. doi: 10.1093/bioinformatics/btv567. PMCID: PMC4708106
Time-Course Analysis of Brain Regional Expression Network Responses to Chronic Intermittent Ethanol and Withdrawal: Implications for Mechanisms Underlying Excessive Ethanol Consumption.
January 5, 2016
Maren L. Smith, Marcelo F. Lopez, Kellie J. Archer, Aaron R. Wolen, Howard C. Becker, Michael F. Miles
2016 PLoS One 11(1):e0146257. doi: 10.137/journal.pone.0146257. PMCID: PMC4701666
Nicotine Enhances the Hypnotic and Hypothermic Effects of Alcohol in the Mouse.
January 1, 2016
Slater CA, Jackson A, Muldoon PP, Dawson A, O'Brien M, Soll LG, Abdullah R, Carroll FI, Tapper AR, Miles MF, Banks ML, Bettinger JC, Damaj IM.
2016 Alcohol Clin Exp Res. 40(1):62-72. doi: 10.1111/acer.12918. PMCID: PMC4700556.
Applying the new genomics to alcohol dependence.
December 1, 2015
Farris SP, Pietrzykowski AZ, Miles MF, O'Brien MA, Sanna PP, Zakhari S, Mayfield RD, Harris RA.
2015 Alcohol. 49(8):825-36. doi: 10.1016/j.alcohol.2015.03.001. PMCID: PMC4586299
Level of response to alcohol as a factor for targeted prevention in college students.
November 1, 2015
Savage JE, Neale Z, Cho SB, Hancock L, Kalmijn JA, Smith TL, Schuckit MA, Donovan KK, Dick DM.
2015 Alcohol Clin Exp Res. 39(11):2215-23. doi: 10.1111/acer.12874. PMCID: PMC4624230.
Patterns of Substance Use Across the First Year of College and Associated Risk Factors.
October 27, 2015
Cho SB, Llaneza DC, Adkins AE, Cooke M, Kendler KS, Clark SL, Dick DM.
2015 Front Psychiatry. 6:152. doi: 10.3389/fpsyt.2015.00152. PMCID: PMC4621385.
DISTMIX: direct imputation of summary statistics for unmeasured SNPs from mixed ethnicity cohorts.
October 1, 2015
Lee D, Bigdeli TB, Williamson VS, Vladimirov VI, Riley BP, Fanous AH, Bacanu SA
2015 Bioinformatics. 31(19):3099-104. doi:10.1093/bioinformatics/btv348. PMCID: PMC4576696.
Integrating mRNA and miRNA Weighted Gene Co-Expression Networks with eQTLs in the Nucleus Accumbens of Subjects with Alcohol Dependence
September 18, 2015
Mamdani M, Williamson V, McMichael GO, Blevins T, Aliev F, Adkins A, Hack L, Bigdeli T, van der Vaart AD, Web BT, Bacanu SA, Kalsi G; COGA Consortium, Kendler KS, Miles MF, Dick D, Riley BP, Dumur C, Vladimirov VI.
2015 PLoS One. 10(9):e0137671. doi: 10.1371/journal.pone.0137671. PMCID: PMC4575063.
Rodent Brain Microinjection to Study Molecular Substrates of Motivated Behavior.
September 16, 2015
Poland RS, Bull C, Syed WA, Bowers MS
2015 J Vis Exp. (103). doi:10.3791/53018. PMCID: PMC4692606.
The stability and predictors of peer group deviance in university students.
September 1, 2015
Kendler KS, Myers J, Dick D.
2015 Soc Psychiatry Psychiatr Epidemiol. 50(9):1463-70. doi: 10.1007/s00127-015-1031-4. PMCID: PMC4546573
Addiction resistance: Definition, validation and association with mastery.
September 1, 2015
Kendler KS, Myers J
2015 Drug Alcohol Depend. 154:236-42. doi:10.1016/j.drugalcdep.2015.06.043. PMCID: PMC4575813.
Oral operant ethanol self-administration in the absence of explicit cues, food restriction, water restriction and ethanol fading in C57BL/6J mice.
August 14, 2015
Stafford AM, Anderson SM, Shelton KL, Brunzell DH
2015 Psychopharmacology (Berl). 232(20):3783-95. doi: 10.1007/s00213-015-4040-9. PMCID: PMC4667783.
Overlapping genetic and environmental influences among men's alcohol consumption and problems, romantic quality and social support.
August 1, 2015
Salvatore JE, Prom-Wormley E, Prescott CA, Kendler KS.
2015 Psychol Med. 45(11):2353-64. doi:10.1017/S003329171500029X. PMCID: PMC4499011
Drosophila and Caenorhabditis elegans as Discovery Platforms for Genes Involved in Human Alcohol Use Disorder.
August 1, 2015
Grotewiel M, Bettinger JC
2015 Alcohol Clin Exp Res. 39(8):1292-311. doi: 10.1111/acer.12785. PMCID: PMC4656040.
The predictive power of family history measures of alcohol and drug problems and internalizing disorders in a college population
July 1, 2015
Kendler KS, Edwards A, Myers J, Cho SB, Adkins A, Dick D.
2015 Am J Med Genet B Neuropsychiatr Genet. 168B(5):337-46. doi: 10.1002/ajmg.b.32320. PMCID: PMC4466079
Translating Alcohol Research: Opportunities and Challenges
June 1, 2015
Batman AM, Miles MF.
2015 Alcohol Res. 37(1):7-14. PMCID: PMC4476605
JEPEG: a summary statistics based tool for gene-level joint testing of functional variants.
April 15, 2015
Lee D, Williamson VS, Bigdeli TB, Riley BP, Fanous AH, Vladimirov VI, Bacanu SA.
2015 Bioinformatics 31(8):1176-82. doi:10.1093/bioinformatics/btu816. PMCID: PMC4393522.
An inexpensive, scalable behavioral assay for measuring ethanol sedation sensitivity and rapid tolerance in Drosophila.
April 15, 2015
Sandhu S, Kollah AP, Lewellyn L, Chan RF, Grotewiel M.
2015 J Vis Exp. (98) e52676. doi: 10.3791/52676.PMCID: PMC4423423
An Assay for Measuring the Effects of Ethanol on the Locomotion Speed of Caenorhabditis elegans
April 9, 2015
Davies AG, Blackwell GG, Raabe RC, Bettinger JC.
2015 J Vis Exp. 2015 Apr 9;(98). doi: 10.3791/52681. PMCID:PMC4476067
Sex differences in the pathways to symptoms of alcohol use disorder: a study of opposite-sex twin pairs.
April 6, 2015
Kendler KS, Edwards AC, Gardner CO
2015 Alcohol Clin Exp Res. 39(6):998-1007. doi: 10.1111/acer.12694. PMCID: PMC4452423.
Differential response of glial fibrillary acidic protein-positive astrocytes in the rat prefrontal cortex following ethanol self-administration.
April 1, 2015
Bull C, Syed WA, Minter SC, Bowers MS
2015 Alcohol Clin Exp Res 39(4):650-8. doi: 10.1111/acer.12683. PMCID: PMC4384186.
The heritability of alcohol use disorders: a meta-analysis of twin and adoption studies.
April 1, 2015
Verhulst B, Neale MC, Kendler KS.
2015 Psychol Med. 45(5):1061-72. doi: 10.1017/S0033291714002165. PMCID: PMC4345133
SWI/SNF chromatin remodeling regulates alcohol response behaviors in Caenorhabditis elegans and is associated with alcohol dependence in humans.
March 10, 2015
Mathies LD, Blackwell GG, Austin MK, Edwards AC, Riley BP, Davies AG, Bettinger JC.
2015 Proc Natl Acad Sci U S A. 112(10):3032-7. doi: 10.1073/pnas.1413451112. PMCID: PMC4364201.
An extended Swedish national adoption study of alcohol use disorder.
March 10, 2015
Kendler KS, Ji J, Edwards AC, Ohlsson H, Sundquist J, Sundquist K
2015 JAMA Psychiatry. 72(3):211-8. doi: 10.1001/jamapsychiatry.2014.2138. PMCID: PMC4351126
KCNN Genes that Encode Small-Conductance Ca2+-Activated K+ Channels Influence Alcohol and Drug Addiction.
March 4, 2015
Padula AE, Griffin WC 3rd, Lopez MF, Nimitvilai S, Cannady R, McGuier NS, Chesler EJ, Miles MF, Williams RW, Randall PK, Woodward JJ, Becker HC, Mulholland PJ.
2015 Neuropsychopharmacology 40(8):1928-39. doi:10.1038/npp.2015.42. PMCID: PMC4839516
Nicotinic receptor contributions to smoking: insights from human studies and animal models.
March 1, 2015
Brunzell DH, Stafford AM, Dixon CI
2015 Curr Addict Rep 2(1):33-46. PMCID: PMC4540370.
Endophenotypes for Alcohol Use Disorder: An Update on the Field
March 1, 2015
Salvatore JE, Gottesman II, Dick DM.
2015 Curr Addict Rep. 2(1):76-90. PMCID: PMC4520241
A novel cholinergic action of alcohol and the development of tolerance to that effect in Caenorhabditis elegans.
January 1, 2015
Hawkins EG, Martin I, Kondo LM, Judy ME, Brings VE, Chan CL, Blackwell GG, Bettinger JC, Davies AG.
2015 Genetics 199(1):135-49. doi: 10.1534/genetics.114.171884. PMCID: PMC4286678.
Targeting the Small- and Intermediate-Conductance Ca-Activated Potassium Channels: The Drug-Binding Pocket at the Channel/Calmodulin Interface.
October 14, 2014
Cui M, Qin G, Yu K, Bowers MS, Zhang M
2014 Neurosignals 22(2):65-78. doi:10.1159/000367896. PMCID: PMC4390548.
The α3β4* nicotinic ACh receptor subtype mediates physical dependence to morphine: mouse and human studies.
October 14, 2014
Muldoon PP, Jackson KJ, Perez E, Harenza JL, Molas S, Rais B, Anwar H, Zaveri NT, Maldonado R, Maskos U, McIntosh JM, Dierssen M, Miles MF, Chen X, De Biasi M, Damaj MI.
2014 Br J Pharmacol. 171(16):3845-57. doi: 10.1111/bph.12741. PMCID: PMC4128047
Molecular and neurologic responses to chronic alcohol use.
October 14, 2014
Costin BN, Miles MF
2014 Handb Clin Neurol 125:157-71. doi: 10.1016/B978-0-444-62619-6.00010-0. PMCID: PMC4412740.
Psychiatric resilience: longitudinal twin study.
October 1, 2015
Amstadter AB, Myers JM, Kendler KS.
2014 Br J Psychiatry. 205(4):275-80. doi: 10.1192/bjp.bp.113.130906. PMCID: PMC4180845
The role of the BK channel in ethanol response behaviors: evidence from model organism and human studies.
September 9, 2014
Bettinger JC, Davies AG
2014 Front Physiol 5:346. doi: 10.3389/fphys.2014.00346. PMCID: PMC4158801.
Socioeconomic status and alcohol-related behaviors in mid- to late adolescence in the Avon Longitudinal Study of Parents and Children.
July 1, 2014
Kendler KS, Gardner CO, Hickman M, Heron J, Macleod J, Lewis G, Dick DM.
2014 J Stud Alcohol Drugs. 75(4):541-5. PMCID: PMC4108596
Romantic relationship status and alcohol use and problems across the first year of college.
July 1, 2014
Salvatore JE, Kendler KS, Dick DM.
2014 J Stud Alcohol Drugs. 75(4):580-9. PMCID: PMC4108599
Contrasting influences of Drosophila white/mini-white on ethanol sensitivity in two different behavioral assays.
June 1, 2014
Chan RF, Lewellyn L, DeLoyht JM, Sennett K, Coffman S, Hewitt M, Bettinger JC, Warrick JM, Grotewiel M.
2014 Alcohol Clin Exp Res. 38(6):1582-93. doi: 10.1111/acer.12421. PMCID: PMC4049357
The boundaries of the internalizing and externalizing genetic spectra in men and women.
February 1, 2014
Kendler KS, Myers J.
2014 Psychol Med. 44(3):647-55. doi: 10.1017/S0033291713000585. PMCID: PMC3825740
Genetic and environmental risk factors for illicit substance use and use disorders: Joint analysis of self and co-twin ratings.
January 1, 2014
Ystrom E, Reichborn-Kjennerud T, Neale MC, Kendler KS.
2014 Behav Genet. 44(1):1-13. doi: 10.1007/s10519-013-9626-6. PMCID: PMC3893354