2024

Neuron enriched extracellular vesicles' MicroRNA expression profiles as a marker of early life alcohol consumption.
Yakovlev V, Lapato DM, Rana P, Ghosh P, Frye R, Roberson-Nay R. Transl Psychiatry. 2024 Apr 4;14(1):176. doi: 10.1038/s41398-024-02874-3. PMID: 38575599

Naturalistic symptom trajectories of atypical anorexia nervosa, anorexia nervosa, and bulimia nervosa in a prospective cohort study of United States college students.
Hagan KE, Johnson A, Venables K, Makara A; Spit for Science Working Group; Haynos AF. Int J Eat Disord. 2024 Feb 2. doi: 10.1002/eat.24152. Online ahead of print. PMID: 38303677

Gut-Liver-Brain Axis and Alcohol Use Disorder: Treatment Potential of Fecal Microbiota Transplantation.
Wolstenholme JT, Duong NK, Brocato ER, Bajaj JS. Alcohol Res. 2024 Feb 1;44(1):01. doi: 10.35946/arcr.v44.1.01. eCollection 2024. PMID: 38322428

A zinc finger transcription factor enables social behaviors while controlling transposable elements and immune response in prefrontal cortex.
Truby NL, Kim RK, Silva GM, Qu X, Picone JA, Alemu R, Atiyeh CN, Neve RL, Liu J, Cui X, Hamilton PJ. Transl Psychiatry. 2024 Jan 25;14(1):59. doi: 10.1038/s41398-024-02775-5. PMID: 38272911

Alcohol Use Disorder-Associated DNA Methylation in the Nucleus Accumbens and Dorsolateral Prefrontal Cortex.
White JD, Minto MS, Willis C, Quach BC, Han S, Tao R, Deep-Soboslay A, Zillich L, Clark SL, van den Oord EJCG, Hyde TM, Mayfield RD, Webb BT, Johnson EO, Kleinman JE, Bierut LJ, Hancock DB. medRxiv [Preprint]. 2024 Jan 17:2024.01.17.23300238. doi: 10.1101/2024.01.17.23300238. PMID: 38293028

Medical and genetic correlates of long-term buprenorphine treatment in the electronic health records.
Niarchou M, Sanchez-Roige S, Reddy IA, Reese TJ, Marcovitz D, Davis LK. Transl Psychiatry. 2024 Jan 10;14(1):20. doi: 10.1038/s41398-023-02713-x. PMID: 38200003

Initial Results from a New College Substance Use Prevention Program Targeting Externalizing and Internalizing Traits.
Choi M, Driver MN, Balcke E, Saunders T, Langberg JM, Dick DM. Subst Use Misuse. 2024;59(3):421-424. doi: 10.1080/10826084.2023.2275565. Epub 2024 Jan 25. PMID: 37897057

2023

Adolescent social housing protects against adult emotional and cognitive deficits and alters the PFC and NAc transcriptome in male and female C57BL/6J mice.
Lodha J, Brocato ER, Nash M, Marcus MM, Pais AC, Pais AB, Miles MF, Wolstenholme JT. Front Neurosci. 2023 Dec 7;17:1287584. doi: 10.3389/fnins.2023.1287584. eCollection 2023. PMID: 38130694

Is pre-college interpersonal trauma associated with cannabis use?
Hicks TA, Bustamante D, Bountress KE, Adkins AE, Svikis DS, Gillespie NA, Dick DM; Spit for Science Working Group; Amstadter AB. J Am Coll Health. 2023 Dec;71(9):2645-2652. doi: 10.1080/07448481.2021.1980399. Epub 2021 Sep 29. PMID: 34586040

Guidelines for Evaluating the Comparability of Down-Sampled GWAS Summary Statistics.
Williams CM, Poore H, Tanksley PT, Kweon H, Courchesne-Krak NS, Londono-Correa D, Mallard TT, Barr P, Koellinger PD, Waldman ID, Sanchez-Roige S, Harden KP, Palmer AA, Dick DM, Karlsson Linnér R. Behav Genet. 2023 Nov;53(5-6):404-415. doi: 10.1007/s10519-023-10152-z. Epub 2023 Sep 15. PMID: 37713023

The longitudinal buffering effects of resilience on alcohol use outcomes.
Cusack SE, Bountress KE, Sheerin CM, Spit For Science Work Group, Dick DM, Amstadter AB. Psychol Trauma. 2023 Sep;15(6):1000-1011. doi: 10.1037/tra0001156. Epub 2021 Nov 29. PMID: 34843351

Bridging the gap between genetic epidemiological research and prevention: A randomized control trial of a novel personalized feedback program for alcohol and cannabis use.
Choi M, Driver MN, Balcke E, Saunders T, Langberg JM, Dick DM. Drug Alcohol Depend. 2023 Aug 1;249:110818. doi: 10.1016/j.drugalcdep.2023.110818. Epub 2023 Jun 7. PMID: 37327509

Interactions between COVID-19 family home disruptions and relationships predicting college students' mental health over time.
Williams CD, DeLaney EN, Moreno O, Santana A, Fuentes L, Muñoz G, Elias MJ, Johnson KF, Peterson RE, Hood KB, Vassileva J, Dick DM, Amstadter AB. J Fam Psychol. 2023 Aug;37(5):592-602. doi: 10.1037/fam0001085. Epub 2023 May 22. PMID: 37213173

Multi-ancestry meta-analysis of tobacco use disorder prioritizes novel candidate risk genes and reveals associations with numerous health outcomes.
Toikumo S, Jennings MV, Pham BK, Lee H, Mallard TT, Bianchi SB, Meredith JJ, Vilar-Ribó L, Xu H, Hatoum AS, Johnson EC, Pazdernik V, Jinwala Z, Pakala SR, Leger BS, Niarchou M, Ehinmowo M; Penn Medicine BioBank, Million Veteran Program, PsycheMERGE Substance Use Disorder Workgroup; Jenkins GD, Batzler A, Pendegraft R, Palmer AA, Zhou H, Biernacka JM, Coombes BJ, Gelernter J, Xu K, Hancock DB, Cox NJ, Smoller JW, Davis LK, Justice AC, Kranzler HR, Kember RL, Sanchez-Roige S. medRxiv [Preprint]. 2023 Sep 18:2023.03.27.23287713. doi: 10.1101/2023.03.27.23287713. PMID: 37034728

Identification of Genetic and Genomic Influences on Progressive Ethanol Consumption in Diversity Outbred Mice.
Smith ML, Sergi Z, Mignogna KM, Rodriguez NE, Tatom Z, MacLeod L, Choi KB, Philip V, Miles MF. bioRxiv [Preprint]. 2023 Sep 16:2023.09.15.554349. doi: 10.1101/2023.09.15.554349. PMID: 37745421

Improving the discovery of rare variants associated with alcohol problems by leveraging machine learning phenotype prediction and functional information.
Ahangari M, Gentry AE, Hassan MF, Nguyen TH, Kendler KS, Bacanu SA, Peterson RE, Riley BP, Webb BT. bioRxiv [Preprint]. 2023 Sep 15:2023.09.11.557163. doi: 10.1101/2023.09.11.557163. PMID: 37745400

Genome-Wide Association Studies of Coffee Intake in UK/US Participants of European Ancestry Uncover Gene-Cohort Influences. Thorpe HHA, Fontanillas P, Pham BK, Meredith JJ, Jennings MV, Courchesne-Krak NS, Vilar-Ribó L, Bianchi SB, Mutz J; 23andMe Research Team; Elson SL, Khokhar JY, Abdellaoui A, Davis LK, Palmer AA, Sanchez-Roige S. medRxiv [Preprint]. 2023 Sep 11:2023.09.09.23295284. doi: 10.1101/2023.09.09.23295284. PMID: 37745582

A multivariate approach to understanding the genetic overlap between externalizing phenotypes and substance use disorders.
Poore HE, Hatoum A, Mallard TT, Sanchez-Roige S, Waldman ID, Palmer AA, Harden KP, Barr PB, Dick DM. Addict Biol. 2023 Sep;28(9):e13319. doi: 10.1111/adb.13319. PMID: 37644899

Investigating genetically stratified subgroups to better understand the etiology of alcohol misuse.
Thijssen AB; Spit for Science Working Group; Dick DM, Posthuma D, Savage JE. Mol Psychiatry. 2023 Jul 25. doi: 10.1038/s41380-023-02174-0. Online ahead of print. PMID: 37488169

Family History and Alcohol Use Outcomes: Examining Transmission of Risk through Impulsivity and the Moderating Role of Organized Sports Participation.
McNamara IA, Soto D, Su J; Spit for Science Working Group; Dick DM. Subst Use Misuse. 2023;58(9):1090-1101. doi: 10.1080/10826084.2023.2205518. Epub 2023 May 17. PMID: 37194673

Correlates of Risk for Disinhibited Behaviors in the Million Veteran Program Cohort.
Barr PB, Bigdeli TB, Meyers JL, Peterson RE, Sanchez-Roige S, Mallard TT, Dick DM, Paige Harden K, Wilkinson A, Graham DP, Nielsen DA, Swann A, Lipsky RK, Kosten T, Aslan M, Harvey PD, Kimbrel NA, Beckham JC. medRxiv [Preprint]. 2023 Jul 11:2023.03.22.23286865. doi: 10.1101/2023.03.22.23286865. PMID: 37034805

Externalizing traits: Shared causalities for COVID-19 and Alzheimer's dementia using Mendelian randomization analysis.
Wang H, Cao M, Xi Y, Cao W, Zhang X, Meng X, Zheng D, Wu L, Wang W, Liu D, Wang Y. PNAS Nexus. 2023 Jun 15;2(6):pgad198. doi: 10.1093/pnasnexus/pgad198. eCollection 2023 Jun. PMID: 37361546

Interactions between COVID-19 family home disruptions and relationships predicting college students' mental health over time.
Williams CD, DeLaney EN, Moreno O, Santana A, Fuentes L, Muñoz G, Elias MJ, Johnson KF, Peterson RE, Hood KB, Vassileva J, Dick DM, Amstadter AB. J Fam Psychol. 2023 Aug;37(5):592-602. doi: 10.1037/fam0001085. PMID: 37213173

CADM2 is implicated in impulsive personality and numerous other traits by genome- and phenome-wide association studies in humans and mice.
Sanchez-Roige S, Jennings MV, Thorpe HHA, Mallari JE, van der Werf LC, Bianchi SB, Huang Y, Lee C, Mallard TT, Barnes SA, Wu JY, Barkley-Levenson AM, Boussaty EC, Snethlage CE, Schafer D, Babic Z, Winters BD, Watters KE, Biederer T; 23andMe Research Team; Mackillop J, Stephens DN, Elson SL, Fontanillas P, Khokhar JY, Young JW, Palmer AA. Transl Psychiatry. 2023 May 12;13(1):167. doi: 10.1038/s41398-023-02453-y. PMID: 37173343

Adolescent binge ethanol impacts H3K36me3 regulation of synaptic genes.
Brocato ER, Wolstenholme JT. Front Mol Neurosci. 2023 Mar 3;16:1082104. doi: 10.3389/fnmol.2023.1082104. eCollection 2023. PMID: 36937047

Identification of candidate genes for nicotine withdrawal in C57BL/6J × DBA/2J recombinant inbred mice.
Smith ML, Mignogna KM, Rokita JL, MacLeod L, Damaj MI, Miles MF. Genes Brain Behav. 2023 Feb 13:e12844. doi: 10.1111/gbb.12844. PMID: 36781202

2022

The Promise and Peril of Genetics.
Dick DM. Curr Dir Psychol Sci. 2022 Dec;31(6):480-485. doi: 10.1177/09637214221112041. Epub 2022 Sep 16. PMID: 36591341

Cultural Socialization and Ethnic-Racial Identity Mediated by Positive and Negative Conversations about Race: Exploring Differences among Asian American, African American, Latinx, Multiracial, and White Students.
Elias MJ, DeLaney EN, Williams CD, Hawa S, Walker CJ, Lozada FT, Su J; Spit for Science Working Group, Dick DM. Identity (Mahwah, N J). 2022;22(4):282-297. doi: 10.1080/15283488.2021.1999815. Epub 2021 Nov 25. PMID: 36467314

A neuropeptide signal confers ethanol state dependency during olfactory learning in Caenorhabditis elegans.
Lindsay JH, Mathies LD, Davies AG, Bettinger JC. Proc Natl Acad Sci USA. 2022 Nov 16;119(46):e2210462119. doi: 10.1073/pnas.2210462119. Epub 2022 Nov 7. PMID: 36343256

Reduced alcohol preference and intake after fecal transplant in patients with alcohol use disorder is transmissible to germ-free mice. 
Wolstenholme JT, Saunders JM, Smith M, Kang JD, Hylemon PB, González-Maeso J, Fagan A, Zhao D, Sikaroodi M, Herzog J, Shamsaddini A, Peña-Rodríguez M, Su L, Tai YL, Zheng J, Cheng PC, Sartor RB, Gillevet PM, Zhou H, Bajaj JS. Nat Commun. 2022 Oct 19;13(1):6198. doi: 10.1038/s41467-022-34054-6. PMID: 36261423

Genetic and environmental etiology of drinking motives in college students. 
Savage JE, Peterson RE, Aliev F; Spit for Science Working Group, Dick DM. Alcohol Clin Exp Res. 2022 Oct;46(10):1783-1796. doi: 10.1111/acer.14930. Epub 2022 Oct 18. PMID: 36256465

Parsing genetically influenced risk pathways: genetic loci impact problematic alcohol use via externalizing and specific risk.
Barr PB, Mallard TT, Sanchez-Roige S, Poore HE, Linnér RK; COGA Collaborators, Waldman ID, Palmer AA, Harden KP, Dick DM. Transl Psychiatry. 2022 Sep 30;12(1):420. doi: 10.1038/s41398-022-02171-x.PMID: 36180423

Differences in genetic correlations between posttraumatic stress disorder and alcohol-related problems phenotypes compared to alcohol consumption-related phenotypes.
Bountress KE, Bustamante D, Subbie-Saenz de Viteri S, Chatzinakos C, Sheerin C, Daskalakis NP, Edenberg HJ; Psychiatric Genomics Consortium Posttraumatic Stress Disorder Working Group, Peterson RE, Webb BT, Meyers J, Amstadter A. Psychol Med. 2022 Sep 30:1-11. doi: 10.1017/S0033291722002999. Online ahead of print.PMID: 36177877

Diagnostic validity of the PC-PTSD screen in college students.
Hawn SE, Cusack SE, George B, Sheerin CM; Spit for Science Working Group, Dick D, Amstadter AB. J Am Coll Health. 2022 Aug-Sep;70(6):1909-1919. doi: 10.1080/07448481.2020.1841768. Epub 2020 Nov 30. PMID: 33253061

COVID-19-Induced Inequalities and Mental Health: Testing the Moderating Roles of Self-rated Health and Race/Ethnicity. 
Johnson KF, Hood KB, Moreno O, Fuentes L, Williams CD, Vassileva J, Amstadter AB, Dick DM; Spit for Science Working Group. J Racial Ethn Health Disparities. 2022 Aug 26:1-11. doi: 10.1007/s40615-022-01389-1. Online ahead of print. PMID: 36018451

Determining the stability of genome-wide factors in BMI between ages 40 to 69 years. 
Gillespie NA, Gentry AE, Kirkpatrick RM, Reynolds CA, Mathur R, Kendler KS, Maes HH, Webb BT, Peterson RE. PLoS Genet. 2022 Aug 11;18(8):e1010303. doi: 10.1371/journal.pgen.1010303. eCollection 2022 Aug. PMID: 35951648

Genes regulating levels of ω-3 long-chain polyunsaturated fatty acids are associated with alcohol use disorder and consumption, and broader externalizing behavior in humans. 
Aliev F, Barr PB, Davies AG, Dick DM, Bettinger JC. Alcohol Clin Exp Res. 2022 Sep;46(9):1657-1664. doi: 10.1111/acer.14916. Epub 2022 Aug 7. PMID: 35904282

Sex-specific effects of psychedelics on prepulse inhibition of startle in 129S6/SvEv mice.
Vohra HZ, Saunders JM, Jaster AM, de la Fuente Revenga M, Jimenez J, Fernández-Teruel A, Wolstenholme JT, Beardsley PM, González-Maeso J.Psychopharmacology (Berl). 2022 Jun;239(6):1649-1664. doi: 10.1007/s00213-021-05913-9. Epub 2021 Aug 4.PMID: 34345931

Role of parental divorce and discord in the intergenerational transmission of alcohol use disorder.
Salvatore JE, Aggen SH, Kendler KS.Drug Alcohol Depend. 2022 May 1;234:109404. doi: 10.1016/j.drugalcdep.2022.109404. Epub 2022 Mar 12.PMID: 35306396

Identification of additional dye tracers for measuring solid food intake and food preference via consumption-excretion in Drosophila.
Shell BC, Grotewiel M.Sci Rep. 2022 Apr 13;12(1):6201. doi: 10.1038/s41598-022-10252-6.PMID: 35418664 Free PMC article.

Polygenic score for cigarette smoking is associated with ever electronic-cigarette use in a college-aged sample.
Cooke ME, Clifford JS, Do EK, Gilman JM, Maes HH, Peterson RE, Prom-Wormley EC, Evins AE, Schuster RM; Spit for Science Working group. Addiction. 2022 Apr;117(4):1071-1078. doi: 10.1111/add.15716. Epub 2021 Nov 3. PMID: 34636095

Coffee and energy drink use patterns in college freshmen: associations with adverse health behaviors and risk factors.
Svikis DS, Dillon PM, Meredith SE, Thacker LR, Polak K, Edwards AC, Pomm D, Dick D, Kendler K; Spit for Science Working Group. BMC Public Health. 2022 Mar 26;22(1):594. doi: 10.1186/s12889-022-13012-3. PMID: 35346128 

Areas of Convergence and Divergence in Adolescent Social Isolation and Binge Drinking: A Review.
Lodha J, Brocato E, Wolstenholme JT. Front Behav Neurosci. 2022 Mar 30;16:859239. doi: 10.3389/fnbeh.2022.859239. eCollection 2022. PMID: 35431830

The COVID-19 pandemic impacts psychiatric outcomes and alcohol use among college students.
Bountress KE, Cusack SE, Conley AH, Aggen SH, The Spit For Science Working Group, Vassileva J, Dick DM, Amstadter AB. Eur J Psychotraumatol. 2022 Feb 14;13(1):2022279. doi: 10.1080/20008198.2021.2022279. eCollection 2022.PMID: 35186215

Depressive Symptoms and Drinking to Cope in Relation to Alcohol Use Outcomes among White and Black/African American College Students.
Taylor NL, Su J; Spit for Science Working Group, Dick DM. Subst Use Misuse. 2022;57(5):708-718. doi: 10.1080/10826084.2022.2034871. Epub 2022 Feb 12. PMID: 35156525

Comparing behavior following binge ethanol in adolescent and adult DBA/2 J mice.
Bent MAM, Pais AC, Wolstenholme JT. Behav Brain Res. 2022 Feb 15;419:113703. doi: 10.1016/j.bbr.2021.113703. Epub 2021 Dec 3.PMID: 34864163

preciseTAD: a transfer learning framework for 3D domain boundary prediction at base-pair resolution.
Stilianoudakis SC, Marshall MA, Dozmorov MG. Bioinformatics. 2022 Jan 12;38(3):621-630. doi: 10.1093/bioinformatics/btab743. PMID: 34741515

A longitudinal mediational investigation of risk pathways among cannabis use, interpersonal trauma exposure, and trauma-related distress.
Hicks TA, Bountress KE, Adkins AE, Svikis DS, Gillespie NA, Dick DM, Spit For Science Working Group, Amstadter AB. Psychol Trauma. 2022 Jan 31. doi: 10.1037/tra0001207. Online ahead of print. PMID: 35099217

Divergent changes: abstinence and higher-frequency substance use increase among racial/ethnic minority young adults during the COVID-19 global pandemic.
Hicks TA, Chartier KG, Buckley TD, Reese D, Working Group TSFS, Vassileva J, Dick DM, Amstadter AB, Peterson RE, Moreno O. Am J Drug Alcohol Abuse. 2022 Jan 2;48(1):88-99. doi: 10.1080/00952990.2021.1995401. Epub 2022 Jan 10.PMID: 35007453

Chloride intracellular channel 4 (CLIC4) expression profile in the mouse medial prefrontal cortex and its regulation by ethanol.
Bogenpohl JW, Weston RM, Foreman TN, Kitchen KE, Miles MF. Alcohol Clin Exp Res. 2022 Jan;46(1):29-39. doi: 10.1111/acer.14754. Epub 2021 Dec 9. PMID: 34839533

2021

A longitudinal study examining the associations between interpersonal trauma and romantic relationships among college students.
Smith RL, Dick DM, Amstadter A, Thomas N; Spit for Science Working Group, Salvatore JE. Dev Psychopathol. 2021 Dec 14:1-12. doi: 10.1017/S0954579421001243. Online ahead of print. PMID: 34903311

preciseTAD: A transfer learning framework for 3D domain boundary prediction at base-pair resolution.
Stilianoudakis SC, Marshall MA, Dozmorov MG. Bioinformatics. 2021 Nov 6;38(3):621-30. doi: 10.1093/bioinformatics/btab743. Online ahead of print. PMID: 34741515.

Genome-wide association study of problematic opioid prescription use in 132,113 23andMe research participants of European ancestry.
Sanchez-Roige S, Fontanillas P, Jennings MV, Bianchi SB, Huang Y, Hatoum AS, Sealock J, Davis LK, Elson SL; 23andMe Research Team, Palmer AA. Mol Psychiatry. 2021 Nov;26(11):6209-6217. doi: 10.1038/s41380-021-01335-3. Epub 2021 Nov 2.PMID: 34728798

Neuroepigenetic consequences of adolescent ethanol exposure.
Brocato E, Wolstenholme JT. Int Rev Neurobiol. 2021;160:45-84. doi: 10.1016/bs.irn.2021.06.008. Epub 2021 Jul 27.PMID: 34696879

Prolonged epigenomic and synaptic plasticity alterations following single exposure to a psychedelic in mice.
de la Fuente Revenga M, Zhu B, Guevara CA, Naler LB, Saunders JM, Zhou Z, Toneatti R, Sierra S, Wolstenholme JT, Beardsley PM, Huntley GW, Lu C, González-Maeso J. Cell Rep. 2021 Oct 19;37(3):109836. doi: 10.1016/j.celrep.2021.109836.PMID: 34686347

Expansion and application of dye tracers for measuring solid food intake and food preference in Drosophila.
Shell BC, Luo Y, Pletcher S, Grotewiel M. Sci Rep. 2021 Oct 8;11(1):20044. doi: 10.1038/s41598-021-99483-7.PMID: 34625601

Is pre-college interpersonal trauma associated with cannabis use?
Hicks TA, Bustamante D, Bountress KE, Adkins AE, Svikis DS, Gillespie NA, Dick DM; Spit for Science Working Group, PhD, Amstadter AB. J Am Coll Health. 2021 Sep 29:1-8. doi: 10.1080/07448481.2021.1980399. Online ahead of print. PMID: 34586040

Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.
Karlsson Linnér R, Mallard TT, Barr PB, Sanchez-Roige S, Madole JW, Driver MN, Poore HE, de Vlaming R, Grotzinger AD, Tielbeek JJ, Johnson EC, Liu M, Rosenthal SB, Ideker T, Zhou H, Kember RL, Pasman JA, Verweij KJH, Liu DJ, Vrieze S; COGA Collaborators, Kranzler HR, Gelernter J, Harris KM, Tucker-Drob EM, Waldman ID, Palmer AA, Harden KP, Koellinger PD, Dick DM. Nat Neurosci. 2021 Oct;24(10):1367-1376. doi: 10.1038/s41593-021-00908-3. Epub 2021 Aug 26. PMID: 34446935

Racial discrimination, depressive symptoms, ethnic-racial identity, and alcohol use among Black American college students.
Su J, Seaton EK, Williams CD, Spit For Science Working Group, Dick DM. Psychol Addict Behav. 2021 Aug;35(5):523-535. doi: 10.1037/adb0000717. PMID: 34424030

Transcriptome analysis of chloride intracellular channel knockdown in Drosophila identifies oxidation-reduction function as possible mechanism of altered sensitivity to ethanol sedation.
Weston RM, Schmitt RE, Grotewiel M, Miles MF. PLoS One. 2021 Jul 6;16(7):e0246224. doi: 10.1371/journal.pone.0246224. eCollection 2021. PMID: 34228751 

Identifying a novel biological mechanism for alcohol addiction associated with circRNA networks acting as potential miRNA sponges.
Vornholt E, Drake J, Mamdani M, McMichael G, Taylor ZN, Bacanu SA, Miles MF, Vladimirov VI. Addict Biol. 2021 Nov;26(6):e13071. doi: 10.1111/adb.13071. Epub 2021 Jun 23. PMID: 34164896

Potential causal effect of posttraumatic stress disorder on alcohol use disorder and alcohol consumption in individuals of European descent: A Mendelian Randomization Study.
Bountress KE, Wendt F, Bustamante D, Agrawal A, Webb B, Gillespie N, Edenberg H, Sheerin C, Johnson E; Psychiatric Genomics Consortium Posttraumatic Stress Disorder Working Group, Polimanti R, Amstadter A. Alcohol Clin Exp Res. 2021 Aug;45(8):1616-1623. doi: 10.1111/acer.14649. Epub 2021 Jun 24. PMID: 34120358

Mapping Pathways by Which Genetic Risk Influences Adolescent Externalizing Behavior: The Interplay Between Externalizing Polygenic Risk Scores, Parental Knowledge, and Peer Substance Use.
Kuo SI, Salvatore JE, Barr PB, Aliev F, Anokhin A, Bucholz KK, Chan G, Edenberg HJ, Hesselbrock V, Kamarajan C, Kramer JR, Lai D, Mallard TT, Nurnberger JI Jr, Pandey G, Plawecki MH, Sanchez-Roige S, Waldman I, Palmer AA; Externalizing Consortium, Dick DM. Behav Genet. 2021 Sep;51(5):543-558. doi: 10.1007/s10519-021-10067-7. Epub 2021 Jun 12. PMID: 34117972

Genetically influenced externalizing and internalizing risk pathways as novel prevention targets.
Dick DM, Saunders T, Balcke E, Driver MN, Neale Z, Vassileva J, Langberg JM. Psychol Addict Behav. 2022 Sep;36(6):595-606. doi: 10.1037/adb0000759. Epub 2021 Jun 10.PMID: 34110842

Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): II. Externalizing superspectrum.
Krueger RF, Hobbs KA, Conway CC, Dick DM, Dretsch MN, Eaton NR, Forbes MK, Forbush KT, Keyes KM, Latzman RD, Michelini G, Patrick CJ, Sellbom M, Slade T, South SC, Sunderland M, Tackett J, Waldman I, Waszczuk MA, Wright AGC, Zald DH, Watson D, Kotov R; HiTOP Utility Workgroup. World Psychiatry. 2021 Jun;20(2):171-193. doi: 10.1002/wps.20844.PMID: 34002506

A longitudinal study of the moderating effects of romantic relationships on the associations between alcohol use and trauma in college students.
Smith RL, Dick DM, Amstadter A, Thomas N; Spit for Science Working Group, Salvatore JE. Addiction. 2021 Nov;116(11):3008-3018. doi: 10.1111/add.15490. Epub 2021 Apr 22. PMID: 33886135

Chromatin conformation capture (Hi-C) sequencing of patient-derived xenografts: analysis guidelines.
Dozmorov MG, Tyc KM, Sheffield NC, Boyd DC, Olex AL, Reed J, Harrell JC. Gigascience. 2021 Apr 21;10(4):giab022. doi: 10.1093/gigascience/giab022.PMID: 33880552

DECO: a framework for jointly analyzing de novo and rare case/control variants, and biological pathways.
Nguyen TH, He X, Brown RC, Webb BT, Kendler KS, Vladimirov VI, Riley BP, Bacanu SA. Brief Bioinform. 2021 Sep 2;22(5):bbab067. doi: 10.1093/bib/bbab067.PMID: 33791774

Mental health disorder symptom prevalence and rates of help-seeking among University-Enrolled, emerging adults.
Williams KDA, Adkins A, Kuo SI, LaRose JG, Utsey SO, Guidry JPD; Spit for Science Working Group, Dick D, Carlyle KE. J Am Coll Health. 2021 Mar 18:1-8. doi: 10.1080/07448481.2021.1873791. Online ahead of print. PMID: 33735596

Risk, Protective, and Associated Factors of Anxiety and Depressive Symptoms and Campus Health Services Utilization Among Black Men on a College Campus.
Williams KDA, Adkins AE, Kuo SI, LaRose JG, Utsey SO, Guidry JPD; Spit for Science Working Group, Dick D, Carlyle KE. J Racial Ethn Health Disparities. 2022 Apr;9(2):505-518. doi: 10.1007/s40615-021-00981-1. Epub 2021 Mar 8. PMID: 33686626

Glucocorticoid receptor modulators decrease alcohol self-administration in male rats.
McGinn MA, Tunstall BJ, Schlosburg JE, Gregory-Flores A, George O, de Guglielmo G, Mason BJ, Hunt HJ, Koob GF, Vendruscolo LF. Neuropharmacology. 2021 May 1;188:108510. doi: 10.1016/j.neuropharm.2021.108510. Epub 2021 Feb 26. PMID: 33647278

Latent Profiles of Alcohol Consumption Among College Students Exposed to Trauma.
Bountress KE, Hawn SE, Dick DM, Amstadter AB; Spit for Science Working Group. J Addict Nurs. 2021 Jan-Mar 01;32(1):3-13. doi: 10.1097/JAN.0000000000000379. PMID: 33646712

Psychiatric genomics research during the COVID-19 pandemic: A survey of Psychiatric Genomics Consortium researchers.
Guintivano J, Dick D, Bulik CM. Am J Med Genet B. Neuropsychiatr Genet. 2021 Jan;186(1):40-49. doi: 10.1002/ajmg.b.32838. Epub 2021 Feb 18. PMID: 33605055

Associations between the CADM2 gene, substance use, risky sexual behavior, and self-control: A phenome-wide association study.
Arends RM, Pasman JA, Verweij KJH, Derks EM, Gordon SD, Hickie I, Thomas NS, Aliev F, Zietsch BP, van der Zee MD, Mitchell BL, Martin NG, Dick DM, Gillespie NA, de Geus EJC, Boomsma DI, Schellekens AFA, Vink JM. Addict Biol. 2021 Nov;26(6):e13015. doi: 10.1111/adb.13015. Epub 2021 Feb 18. PMID: 33604983

Increasing the resolution and precision of psychiatric genome-wide association studies by re-imputing summary statistics using a large, diverse reference panel.
Chatzinakos C, Lee D, Cai N, Vladimirov VI, Webb BT, Riley BP, Flint J, Kendler KS, Ressler KJ, Daskalakis NP, Bacanu SA. Am J Med Genet B Neuropsychiatr Genet. 2021 Jan;186(1):16-27. doi: 10.1002/ajmg.b.32834. Epub 2021 Feb 11. PMID: 33576176

Tyramine synthesis, vesicular packaging, and the SNARE complex function coordinately in astrocytes to regulate Drosophila alcohol sedation.
Lee KM, Talikoti A, Shelton K, Grotewiel M. Addict Biol. 2021 Jul;26(4):e13019. doi: 10.1111/adb.13019. Epub 2021 Feb 3. PMID: 33538092

GCSscore: an R package for differential gene expression analysis in Affymetrix/Thermo-Fisher whole transcriptome microarrays.
Harris GM, Abbas S, Miles MF. BMC Genomics. 2021 Feb 1;22(1):96. doi: 10.1186/s12864-021-07370-2. PMID: 33522903

Cannabis use in college: Genetic predispositions, peers, and activity participation.
Thomas NS, Salvatore JE, Gillespie NA, Aliev F, Ksinan AJ, Dick DM; Spit for Science Working Group. Drug Alcohol Depend. 2021 Feb 1;219:108489. doi: 10.1016/j.drugalcdep.2020.108489. Epub 2020 Dec 21. PMID: 33373877

2020

Interest in Genetic Feedback for Alcohol Use Disorder and Related Substance Use and Psychiatric Outcomes among Young Adults.
Driver MN, Kuo SI, Dick DM, On Behalf Of The Spit For Science Working Group. Brain Sci. 2020 Dec 18;10(12):1007. doi: 10.3390/brainsci10121007. PMID: 33352962

Network preservation reveals shared and unique biological processes associated with chronic alcohol abuse in NAc and PFC.
Vornholt E, Drake J, Mamdani M, McMichael G, Taylor ZN, Bacanu SA, Miles MF, Vladimirov VI. PLoS One. 2020 Dec 17;15(12):e0243857. doi: 10.1371/journal.pone.0243857. eCollection 2020. PMID: 33332381

The Associations Between Sexual Victimization and Health Outcomes Among LGBQA College Students: Examining the Moderating Role of Social Support.
DeLaney EN, Williams CD, Mosley DV, Hawn SE, Dick DM. J Interpers Violence. 2022 Jun;37(11-12):NP10393-NP10417. doi: 10.1177/0886260520978179. Epub 2020 Dec 8. PMID: 33289453

Trauma exposure, alcohol consumption, and sleep quality: a latent growth curve model.
Cusack SE, Bountress KE, Lind MJ, Hawn SE; Spit for Science Working Group, Dick DM, Amstadter AB.  J Am Coll Health. 2022 Oct;70(7):2126-2134. doi: 10.1080/07448481.2020.1845181. Epub 2020 Dec 1.PMID: 33258742

Sex-specific risk profiles for substance use among college students.
Martin CE, Ksinan AJ, Moeller FG, Dick D; Spit for Science Working Group. Brain Behav. 2021 Feb;11(2):e01959. doi: 10.1002/brb3.1959. Epub 2020 Nov 21. PMID: 33222410

Assessing the Role of Long Noncoding RNA in Nucleus Accumbens in Subjects With Alcohol Dependence.
Drake J, McMichael GO, Vornholt ES, Cresswell K, Williamson V, Chatzinakos C, Mamdani M, Hariharan S, Kendler KS, Kalsi G, Riley BP, Dozmorov M, Miles MF, Bacanu SA, Vladimirov VI. Alcohol Clin Exp Res. 2020 Dec;44(12):2468-2480. doi: 10.1111/acer.14479. Epub 2020 Nov 27. PMID: 33067813

TWAS pathway method greatly enhances the number of leads for uncovering the molecular underpinnings of psychiatric disorders.
Chatzinakos C, Georgiadis F, Lee D, Cai N, Vladimirov VI, Docherty A, Webb BT, Riley BP, Flint J, Kendler KS, Daskalakis NP, Bacanu SA. Am J Med Genet B Neuropsychiatr Genet. 2020 Dec;183(8):454-463. doi: 10.1002/ajmg.b.32823. Epub 2020 Sep 21. PMID: 32954640

Adolescent low-dose ethanol drinking in the dark increases ethanol intake later in life in C57BL/6J, but not DBA/2J mice.
Wolstenholme JT, Younis RM, Toma W, Damaj MI. Alcohol. 2020 Dec;89:85-91. doi: 10.1016/j.alcohol.2020.08.005. Epub 2020 Aug 26. PMID: 32860857

The Relationship between Pet Ownership, Social Support, and Internalizing Symptoms in Students from the First to Fourth Year of College.
Barker SB, Schubert CM, Barker RT, Kuo SI, Kendler KS, Dick DM. Appl Dev Sci. 2020;24(3):279-293. doi: 10.1080/10888691.2018.1476148. Epub 2018 Jul 24. PMID: 32742161

Associations between ethnic-racial identity and alcohol problems among diverse emerging adults.
Walker CJ, Derlan Williams C, Cage J, DeLaney EN, Lozada FT; Spit for Science Working Group, Dick DM. J Ethn Subst Abuse. 2022 Apr-Jun;21(2):638-661. doi: 10.1080/15332640.2020.1793865. Epub 2020 Jul 22. PMID: 32697621

SpectralTAD: an R package for defining a hierarchy of topologically associated domains using spectral clustering.
Cresswell KG, Stansfield JC, Dozmorov MG. BMC Bioinformatics. 2020 Jul 20;21(1):319. doi: 10.1186/s12859-020-03652-w. PMID: 32689928

Examination of a novel measure of trauma-related drinking to cope.
Hawn SE, Aggen SH, Cusack SE; Spit for Science Working Group, Dick D, Amstadter AB. J Clin Psychol. 2020 Oct;76(10):1938-1964. doi: 10.1002/jclp.22972. Epub 2020 Jun 1. PMID: 32478444

Brain regional gene expression network analysis identifies unique interactions between chronic ethanol exposure and consumption.
Smith ML, Lopez MF, Wolen AR, Becker HC, Miles MF. PLoS One. 2020 May 29;15(5):e0233319. doi: 10.1371/journal.pone.0233319. eCollection 2020. PMID: 32469986.

Mental health and sleep disparities in an urban college sample: A longitudinal examination of White and Black students.
Dzierzewski JM, Ravyts SG, Dautovich ND, Perez E, Schreiber D, Rybarczyk BD. J Clin Psychol. 2020 Oct;76(10):1972-1983. doi: 10.1002/jclp.22974. Epub 2020 May 14. PMID: 32410237

Population Attributable Fraction of Early Age of Onset of Alcohol Use in Alcohol Abuse and Dependence: A 3-Year Follow-Up Study in University Students.
Caamano-Isorna F, Adkins A, Aliev F, Moure-Rodríguez L, Dick DM. Int J Environ Res Public Health. 2020 Mar 24;17(6):2159. doi: 10.3390/ijerph17062159. PMID: 32213910

E-cigarette use is prospectively associated with initiation of cannabis among college students.
Ksinan AJ, Spindle TR, Thomas NS, Eissenberg T; Spit for Science Working group, Dick DM. Addict Behav. 2020 Jul;106:106312. doi: 10.1016/j.addbeh.2020.106312. Epub 2020 Jan 11. PMID: 32120197

Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium.
Polimanti R, Walters RK, Johnson EC, McClintick JN, Adkins AE, Adkins DE, Bacanu SA, Bierut LJ, Bigdeli TB, Brown S, Bucholz KK, Copeland WE, Costello EJ, Degenhardt L, Farrer LA, Foroud TM, Fox L, Goate AM, Grucza R, Hack LM, Hancock DB, Hartz SM, Heath AC, Hewitt JK, Hopfer CJ, Johnson EO, Kendler KS, Kranzler HR, Krauter K, Lai D, Madden PAF, Martin NG, Maes HH, Nelson EC, Peterson RE, Porjesz B, Riley BP, Saccone N, Stallings M, Wall TL, Webb BT, Wetherill L; Psychiatric Genomics Consortium Substance Use Disorders Workgroup, Edenberg HJ, Agrawal A, Gelernter J. Mol Psychiatry. 2020 Aug;25(8):1673-1687. doi: 10.1038/s41380-020-0677-9. Epub 2020 Feb 26. PMID: 32099098

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies.
Munn-Chernoff MA, Johnson EC, Chou YL, Coleman JRI, Thornton LM, Walters RK, Yilmaz Z, Baker JH, Hübel C, Gordon S, Medland SE, Watson HJ, Gaspar HA, Bryois J, Hinney A, Leppä VM, Mattheisen M, Ripke S, Yao S, Giusti-Rodríguez P, Hanscombe KB, Adan RAH, Alfredsson L, Ando T, Andreassen OA, Berrettini WH, Boehm I, Boni C, Boraska Perica V, Buehren K, Burghardt R, Cassina M, Cichon S, Clementi M, Cone RD, Courtet P, Crow S, Crowley JJ, Danner UN, Davis OSP, de Zwaan M, Dedoussis G, Degortes D, DeSocio JE, Dick DM, Dikeos D, Dina C, Dmitrzak-Weglarz M, Docampo E, Duncan LE, Egberts K, Ehrlich S, Escaramís G, Esko T, Estivill X, Farmer A, Favaro A, Fernández-Aranda F, Fichter MM, Fischer K, Föcker M, Foretova L, Forstner AJ, Forzan M, Franklin CS, Gallinger S, Giegling I, Giuranna J, Gonidakis F, Gorwood P, Gratacos Mayora M, Guillaume S, Guo Y, Hakonarson H, Hatzikotoulas K, Hauser J, Hebebrand J, Helder SG, Herms S, Herpertz-Dahlmann B, Herzog W, Huckins LM, Hudson JI, Imgart H, Inoko H, Janout V, Jiménez-Murcia S, Julià A, Kalsi G, Kaminská D, Karhunen L, Karwautz A, Kas MJH, Kennedy JL, Keski-Rahkonen A, Kiezebrink K, Kim YR, Klump KL, Knudsen GPS, La Via MC, Le Hellard S, Levitan RD, Li D, Lilenfeld L, Lin BD, Lissowska J, Luykx J, Magistretti PJ, Maj M, Mannik K, Marsal S, Marshall CR, Mattingsdal M, McDevitt S, McGuffin P, Metspalu A, Meulenbelt I, Micali N, Mitchell K, Monteleone AM, Monteleone P, Nacmias B, Navratilova M, Ntalla I, O'Toole JK, Ophoff RA, Padyukov L, Palotie A, Pantel J, Papezova H, Pinto D, Rabionet R, Raevuori A, Ramoz N, Reichborn-Kjennerud T, Ricca V, Ripatti S, Ritschel F, Roberts M, Rotondo A, Rujescu D, Rybakowski F, Santonastaso P, Scherag A, Scherer SW, Schmidt U, Schork NJ, Schosser A, Seitz J, Slachtova L, Slagboom PE, Slof-Op't Landt MCT, Slopien A, Sorbi S, Świątkowska B, Szatkiewicz JP, Tachmazidou I, Tenconi E, Tortorella A, Tozzi F, Treasure J, Tsitsika A, Tyszkiewicz-Nwafor M, Tziouvas K, van Elburg AA, van Furth EF, Wagner G, Walton E, Widen E, Zeggini E, Zerwas S, Zipfel S, Bergen AW, Boden JM, Brandt H, Crawford S, Halmi KA, Horwood LJ, Johnson C, Kaplan AS, Kaye WH, Mitchell J, Olsen CM, Pearson JF, Pedersen NL, Strober M, Werge T, Whiteman DC, Woodside DB, Grove J, Henders AK, Larsen JT, Parker R, Petersen LV, Jordan J, Kennedy MA, Birgegård A, Lichtenstein P, Norring C, Landén M, Mortensen PB, Polimanti R, McClintick JN, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Degenhardt F, Docherty AR, Edwards AC, Foo JC, Fox L, Frank J, Hack LM, Hartmann AM, Hartz SM, Heilmann-Heimbach S, Hodgkinson C, Hoffmann P, Hottenga JJ, Konte B, Lahti J, Lahti-Pulkkinen M, Lai D, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Meyers JL, Milaneschi Y, Palviainen T, Peterson RE, Ryu E, Saccone NL, Salvatore JE, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang JC, Webb BT, Wedow R, Wetherill L, Wills AG, Zhou H, Boardman JD, Chen D, Choi DS, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Frye MA, Gäebel W, Hayward C, Ising M, Keyes M, Kiefer F, Koller G, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Männistö S, Müller-Myhsok B, Murray AD, Nurnberger JI, Preuss U, Räikkönen K, Reynolds MD, Ridinger M, Scherbaum N, Schuckit MA, Soyka M, Treutlein J, Witt SH, Wodarz N, Zill P, Adkins DE, Boomsma DI, Bierut LJ, Brown SA, Bucholz KK, Costello EJ, de Wit H, Diazgranados N, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AM, Goldman D, Grucza RA, Hancock DB, Harris KM, Hesselbrock V, Hewitt JK, Hopfer CJ, Iacono WG, Johnson EO, Karpyak VM, Kendler KS, Kranzler HR, Krauter K, Lind PA, McGue M, MacKillop J, Madden PAF, Maes HH, Magnusson PKE, Nelson EC, Nöthen MM, Palmer AA, Penninx BWJH, Porjesz B, Rice JP, Rietschel M, Riley BP, Rose RJ, Shen PH, Silberg J, Stallings MC, Tarter RE, Vanyukov MM, Vrieze S, Wall TL, Whitfield JB, Zhao H, Neale BM, Wade TD, Heath AC, Montgomery GW, Martin NG, Sullivan PF, Kaprio J, Breen G, Gelernter J, Edenberg HJ, Bulik CM, Agrawal A. Addict Biol. 2021 Jan;26(1):e12880. doi: 10.1111/adb.12880. Epub 2020 Feb 16. PMID: 32064741

Associations between major depressive symptoms and drinking onset: Do sex and age matter?
Cheng HG, Kendler KS, Edwards AC. J Affect Disord. 2020 Apr 1;266:549-555. doi: 10.1016/j.jad.2020.01.176. Epub 2020 Jan 29. PMID: 32056925

Trauma-related drinking to cope: A novel approach to the self-medication model.
Hawn SE, Bountress KE, Sheerin CM, Dick DM, Amstadter AB. Psychol Addict Behav. 2020 May;34(3):465-476. doi: 10.1037/adb0000552. Epub 2020 Feb 6. PMID: 32027148

Chronic repeated predatory stress induces resistance to quinine adulteration of ethanol in male mice.
Shaw GA, Bent MAM, Council KR, Pais AC, Amstadter A, Wolstenholme JT, Miles MF, Neigh GN. Behav Brain Res. 2020 Mar 16;382:112500. doi: 10.1016/j.bbr.2020.112500. Epub 2020 Jan 21. PMID: 31978491

Polygenic contributions to alcohol use and alcohol use disorders across population-based and clinically ascertained samples.
Johnson EC, Sanchez-Roige S, Acion L, Adams MJ, Bucholz KK, Chan G, Chao MJ, Chorlian DB, Dick DM, Edenberg HJ, Foroud T, Hayward C, Heron J, Hesselbrock V, Hickman M, Kendler KS, Kinreich S, Kramer J, Kuo SI, Kuperman S, Lai D, McIntosh AM, Meyers JL, Plawecki MH, Porjesz B, Porteous D, Schuckit MA, Su J, Zang Y, Palmer AA, Agrawal A, Clarke TK, Edwards AC. Psychol Med. 2021 May;51(7):1147-1156. doi: 10.1017/S0033291719004045. Epub 2020 Jan 20. PMID: 31955720.

Posttraumatic stress disorder symptoms, relationship quality, and risky alcohol use among trauma-exposed students.
Paltell KC, Smith RL, Kansky J, Cox CM, Amstadter AB, Dick D, The Spit For Science Working Group, Salvatore JE, Berenz EC. Addict Behav. 2020 Mar;102:106216. doi: 10.1016/j.addbeh.2019.106216. Epub 2019 Nov 19. PMID: 31838368

Reasons for Transition From Electronic Cigarette Use to Cigarette Smoking Among Young Adult College Students.
Hiler M, Spindle TR, Dick D, Eissenberg T, Breland A, Soule E. J Adolesc Health. 2020 Jan;66(1):56-63. doi: 10.1016/j.jadohealth.2019.09.003. Epub 2019 Nov 5. PMID: 31699605

Marriage and reductions in men's alcohol, tobacco, and cannabis use.
Salvatore JE, Gardner CO, Kendler KS. Psychol Med. 2020 Nov;50(15):2634-2640. doi: 10.1017/S0033291719002964. Epub 2019 Nov 5. PMID: 31685061

Precollege and New-Onset College Interpersonal Trauma as Predictors of Baseline and Changes in Alcohol Use Disorder Symptoms During College.
Bountress KE, Bustamante D, Sheerin C, Dick DM; Spit for Science Working Group, Amstadter AB. J Interpers Violence. 2021 Nov;36(21-22):10842-10852. doi: 10.1177/0886260519883864. Epub 2019 Oct 24. PMID: 31646942