Grotewiel Head Shot Full

Lead, Center Project 2
Department of Human & Molecular Genetics
Virginia Commonwealth University
Phone: 804-628-4086

Genetic pathways that influence ethanol sedation sensitivity in Drosophila, integration of invertebrate and human data on alcohol behavior

Adkins, A. E., L. M. Hack, T. B. Bigdeli, V. S. Williamson, G. O. McMichael, M. Mamdani, A. C. Edwards, F. Aliev, R. F. Chan, P. Bhandari, R. C. Raabe, J. T. Alaimo, G. G. Blackwell, A. Moscati, R. S. Poland, B. Rood, D. G. Patterson, D. Walsh, C. Collaborative Study of the Genetics of Alcoholism, J. B. Whitfield, G. Zhu, G. W. Montgomery, A. K. Henders, N. G. Martin, A. C. Heath, P. A. F. Madden, J. Frank, M. Ridinger, N. Wodarz, M. Soyka, P. Zill, M. Ising, M. M. Nothen, F. Kiefer, M. Rietschel, C. German Study of the Genetics of Addiction, J. Gelernter, R. Sherva, R. Koesterer, L. Almasy, H. Zhao, H. R. Kranzler, L. A. Farrer, B. S. Maher, C. A. Prescott, D. M. Dick, S. A. Bacanu, L. D. Mathies, A. G. Davies, V. I. Vladimirov, M. Grotewiel, M. S. Bowers, J. C. Bettinger, B. T. Webb, M. F. Miles, K. S. Kendler and B. P. Riley (2017) "Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms", Alcoholism: Clinical and Experimental Research, 41(5): 911-928.

Glinton, K. E., P. J. Benke, M. A. Lines, M. T. Geraghty, P. Chakraborty, O. Y. Al-Dirbashi, Y. Jiang, A. D. Kennedy, M. S. Grotewiel, V. R. Sutton, S. H. Elsea and A. W. El-Hattab (2018) "Disturbed phospholipid metabolism in serine biosynthesis defects revealed by metabolomic profiling", Molecular Genetics and Metabolism, 123(3): 309-316.

Shell, B.C, R. E. Schmitt, K. M. Lee, J. C. Johnson, B. Y. Chung, S. D. Pletcher and M. Grotewiel (2018) “Measurement of solid food intake in Drosophila via consumption-excretion of a dye tracer”, Scientific Reports, 8:115336.

Schmitt, R. E., M. R. Messick, B. C. Shell, E. K. Dunbar, H.-F. Fang, K. L. Shelton, B. J. Venton, S. D. Pletcher, M. Grotewiel (2019) “Dietary yeast influences ethanol sedation in Drosophila via serotonergic neuron function”, Addiction Biology, e12779.

Lee, K. M., L. D. Mathies and M. Grotewiel (2019) “Cysteine proteinase 1 regulates Drosophila alcohol sedation by functioning in adult cortex glia”, Communications Biology, 2:252.

Schmitt, R. E., B. C. Shell, K. M. Lee, K. L. Shelton, L. D. Mathies, A. C. Edwards and M. Grotewiel (2019) Convergent evidence from humans and Drosophila melanogaster implicates the transcription factor MEF2B/Mef2 in alcohol sensitivity”, Alcoholism: Clinical and Experimental Research, 43(9): 1872-1886.

Lee, K. M., A. Talikoti, K. Shelton and M. Grotewiel (2021). “Tyramine synthesis, vesicular packaging and the SNARE complex function coordinately in astrocytes to regulate Drosophila alcohol sedation”, Addiction Biology, e13019.

Weston, R.M., R. Schmitt, M. Grotewiel and M.F. Miles (2021) “Drosophila Clic regulates ethanol sedation sensitivity and oxidation-reduction processes”, PLoS ONE, 16(7), e0246224.

Shell, B.C., Y. Luo, S. Pletcher and M. Grotewiel (2021) “Expansion and application of dye tracers for measuring solid food intake and food preference in Drosophila”, Scientific Reports, 11:20044.

Shell, B.C. and M. Grotewiel (2022) “Identification of additional dye tracers for measuring solid food intake and food preference in Drosophila”, Scientific Reports, 12:6201.

Grotewiel Lab 2016