NIAAA-funded P50 Specialized Alcohol Research Center
Cross-Species Investigation of Gene Networks For Ethanol-Related Behaviors
Michael Miles
Novel gene networks modulating progressive ethanol consumption in DO mice
Jill Bettinger and Andrew Davies
Molecular mechanisms of acute ethanol behaviors in C. elegans
Amy Lasek
Chromatin remodeling mechanisms in alcohol use disorder
Danielle Dick and Fazil Aliev
Human studies to identify genes and characterize risk pathways involved in alcohol related outcomes
Brien Riley, Silviu-Alin Bacanu, and T. Hoang Nguyen
Fine mapping of Alcohol Use Disorder
Michael Miles and Jill Bettinger
Administrative Core
Mikhail Dozmorov and Silviu-Alin Bacanu
Data Analysis, Integration and Resource Sharing Component
Jennifer T. Wolstenholme and Mike Grotewiel
Animal Behavior Core
Amy Lasek
Pilot Core
Current and Past Pilot Projects
Elvin Price
Investigating the Relationship Between Alcohol Use, Blood Pressure Phenotypes, and Genetics in African Americans
B. Todd Webb
Exploring the role of human non-SNP genetic variation on AUD risk to inform cross-species investigations
James Bjork and Alexis Edwards
The role of neurocognition in polygenic risk for alcohol use disorder and comorbidities
Joel Schlosburg
Dissection of the Acute and Dependent Responses to Ethanol in Rats Lacking Fatty Acid Amide Hydrolase
Amy Lasek
Interactions between the chromatin remodeling protein SMARCA4 and the transcription factor STAT3 in gene expression and ethanol consumption
Brien Riley
Establishing protocols for ethanol treatment of induced pluripotent stem cell (iPSC) derived dopaminergic and glutamatergic neurons
Maren Smith
Novel transcriptomic studies on DO mice liver tissue following intermittent ethanol access consumption
Jennifer Wolstenholme
Testing gut-liver-brain axis using fecal microbiota transplant in mice
Roxann Roberson-Nay
Investigating the relationship between alcohol consumption rates and neuron-enriched exosomal microRNA
Michael Miles
Expansion of RNA-Seq studies of DO mice undergoing intermittent ethanol access
Peter Hamilton
Identification of the transcripts affected by dysregulating the nucleus accumbens KRAB-domain containing zinc finger proteins in the ethanol- exposed brain
External Advisory Board
Arpana Agrawal, Ph.D.
Washington University School of Medicine, St. Louis
Nigel S. Atkinson, Ph.D.
University of Texas at Austin
Victor M. Hesselbrock, Ph.D.
University of Connecticut School of Medicine
Abraham A. Palmer, Ph.D.
University of California San Diego
Robert Williams, Ph.D.
University of Tennessee Health Science Center
Internal Advisory Board
Kenneth S. Kendler, M.D.
Virginia Commonwealth University
Gerard F. Moeller, M.D.
Virginia Commonwealth University
Arun J Sanyal, M.D.
Virginia Commonwealth University
Sarah Spiegel, Ph.D.
Virginia Commonwealth University
Robert A. Winn, M.D.
Virginia Commonwealth University