Silhouette

Co-Investigator, Analytic and Informatics Core
Associate Professor, Department of Psychiatry
Virginia Commonwealth University
E-mail: silviu-alin.bacanu@vcuhealth.org
Phone: 804-828-7553

Statistical and psychiatric genetics

Sekar A, Bialas AR, de Rivera H, Davis A, Hammond TR, Kamitaki N, Tooley K, Presumey J, Baum M, Van Doren V, Genovese G, Rose SA, Handsaker RE; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Daly MJ, Carroll MC, Stevens B, McCarroll SA. Schizophrenia risk from complex variation of complement component 4. Nature. 2016 Feb 11; 530(7589):177-83. doi: 10.1038/nature16549. Epub 2016 Jan 27. PubMed PMID: 26814963; PubMed Central PMCID: PMC4752392. 

Loh PR, Bhatia G, Gusev A, Finucane HK, Bulik-Sullivan BK, Pollack SJ; Schizophrenia Working Group of Psychiatric Genomics Consortium, de Candia TR, Lee SH, Wray NR, Kendler KS, O'Donovan MC, Neale BM, Patterson N, Price AL. Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis. Nat Genet. 2015 Dec; 47(12):1385-92. doi: 10.1038/ng.3431. Epub 2015 Nov 2. PubMed PMID: 26523775; PubMed Central PMCID: PMC4666835.

Vilhjálmsson BJ, Yang J, Finucane HK, Gusev A, Lindström S, Ripke S, Genovese G, Loh PR, Bhatia G, Do R, Hayeck T, Won HH; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE) study, Kathiresan S, Pato M, Pato C, Tamimi R, Stahl E, Zaitlen N, Pasaniuc B, Belbin G, Kenny EE, Schierup MH, De Jager P, Patsopoulos NA, McCarroll S, Daly M, Purcell S, Chasman D, Neale B, Goddard M, Visscher PM, Kraft P, Patterson N, Price AL. Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores. Am J Hum Genet. 2015 Oct 1; 97(4):576-92. doi: 10.1016/j.ajhg.2015.09.001. PubMed PMID: 26430803; PubMed Central PMCID: PMC4596916.

Edwards AC, Bigdeli TB, Docherty AR, Bacanu S, Lee D, de Candia TR, Moscati A, Thiselton DL, Maher BS, Wormley BK; Molecular Genetics of Schizophrenia Collaboration (MGS), Walsh D, O'Neill FA, Kendler KS, Riley BP, Fanous AH. Meta-analysis of Positive and Negative Symptoms Reveals Schizophrenia Modifier Genes. Schizophr Bull. 2016 Mar; 42(2):279-87. doi: 10.1093/schbul/sbv119. Epub 2015 Aug 27. PubMed PMID: 26316594; PubMed Central PMCID: PMC4753595. 

CONVERGE consortium. Sparse whole-genome sequencing identifies two loci for major depressive disorder. Nature. 2015 Jul 30; 523(7562):588-91. doi: 10.1038/nature14659. Epub 2015 Jul 15. PubMed PMID: 26176920; PubMed Central PMCID: PMC4522619. 

Docherty AR, Bigdeli TB, Edwards AC, Bacanu S, Lee D, Neale MC, Wormley BK, Walsh D, O'Neill FA, Riley BP, Kendler KS, Fanous AH. Genome-wide gene pathway analysis of psychotic illness symptom dimensions based on a new schizophrenia-specific model of the OPCRIT. Schizophr Res. 2015 May; 164(1-3):181-6. doi: 10.1016/j.schres.2015.02.013. Epub 2015 Mar 13. PubMed PMID: 25778617; PubMed Central PMCID: PMC4409533. 

Bulik-Sullivan BK, Loh PR, Finucane HK, Ripke S, Yang J; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Patterson N, Daly MJ, Price AL, Neale BM. LD Score regression distinguishes confounding from polygenicity in genome-wide association studies. Nat Genet. 2015 Mar; 47(3):291-5. doi: 10.1038/ng.3211. Epub 2015 Feb 2. PubMed PMID: 25642630; PubMed Central PMCID: PMC4495769. 

Gusev A, Lee SH, Trynka G, Finucane H, Vilhjálmsson BJ, Xu H, Zang C, Ripke S, Bulik-Sullivan B, Stahl E; Schizophrenia Working Group of the Psychiatric Genomics Consortium; SWE-SCZ Consortium, Kähler AK, Hultman CM, Purcell SM, McCarroll SA, Daly M, Pasaniuc B, Sullivan PF, Neale BM, Wray NR, Raychaudhuri S, Price AL; Schizophrenia Working Group of the Psychiatric Genomics Consortium; SWE-SCZ Consortium. Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases. Am J Hum Genet. 2014 Nov 6; 95(5):535-52. doi: 10.1016/j.ajhg.2014.10.004. Epub 2014 Nov 6. PubMed PMID: 25439723; PubMed Central PMCID: PMC4225595. 

Schizophrenia Working Group of the Psychiatric Genomics Consortium. Biological insights from 108 schizophrenia-associated genetic loci. Nature. 2014 Jul 24; 511(7510):421-7. doi: 10.1038/nature13595. Epub 2014 Jul 22. PubMed PMID: 25056061; PubMed Central PMCID: PMC4112379.