Darlene H. Brunzell

Co-Investigator, Rodent Behavioral Core
Associate Professor, Department of Pharmacology & Toxicology
Virginia Commonwealth University
E-mail: darlene.brunzell@vcuhealth.org
Phone: 804-628-7584

Neuropharmacology of drugs of abuse and mental illness; Mechanisms of learning and memory; Developmental Toxicology; Sex differences

Sanchez V, Lycas MD, Lynch WJ, Brunzell DH. Wheel running exercise attenuates vulnerability to self-administer nicotine in rats. Drug Alcohol Depend. 2015 Nov 1; 156:193-8. doi:  10.1016/j.drugalcdep.2015.09.022. Epub 2015 Sep 28. PubMed PMID: 26433561; PubMed Central PMCID: PMC4633318. 

Brunzell DH, Stafford AM, Dixon CI. Nicotinic receptor contributions to smoking: insights from human studies and animal models. Curr Addict Rep. 2015 Mar; 2(1):33-46. PubMed PMID: 26301171; PubMed Central PMCID: PMC4540370. 

Stafford AM, Anderson SM, Shelton KL, Brunzell DH. Oral operant ethanol self-administration in the absence of explicit cues, food restriction, water restriction and ethanol fading in C57BL/6J mice. Psychopharmacology (Berl). 2015 Oct; 232(20):3783-95. doi: 10.1007/s00213-015-4040-9. Epub 2015 Aug 14. PubMed PMID: 26268145; PubMed Central PMCID: PMC4667783. 

Sanjakdar SS, Maldoon PP, Marks MJ, Brunzell DH, Maskos U, McIntosh JM, Bowers MS, Damaj MI. Differential roles of α6β2* and α4β2* neuronal nicotinic receptors in nicotine- and cocaine-conditioned reward in mice. Neuropsychopharmacology. 2015 Jan; 40(2):350-60. doi: 10.1038/npp.2014.177. Epub 2014 Jul 18. PubMed PMID: 25035086; PubMed Central PMCID: PMC4443947. 

Brunzell DH, McIntosh JM, Papke RL. Diverse strategies targeting α7 homomeric and α6β2* heteromeric nicotinic acetylcholine receptors for smoking cessation. Ann N Y Acad Sci. 2014 Oct; 1327:27-45. doi: 10.1111/nyas.12421. Epub 2014 Apr 14. Review. PubMed PMID: 24730978; PubMed Central PMCID: PMC4197117. 

Sanchez V, Moore CF, Brunzell DH, Lynch WJ. Sex differences in the effect of wheel running on subsequent nicotine-seeking in a rat adolescent-onset self-administration model. Psychopharmacology (Berl). 2014 Apr; 231(8):1753-62. doi: 10.1007/s00213-013-3359-3. Epub 2013 Nov 24. PubMed PMID: 24271035; PubMed Central PMCID: PMC3969388. 

Wang Y, Lee JW, Oh G, Grady SR, McIntosh JM, Brunzell DH, Cannon JR, Drenan RM. Enhanced synthesis and release of dopamine in transgenic mice with gain-of-function α6* nAChRs. J Neurochem. 2014 Apr; 129(2):315-27. doi: 10.1111/jnc.12616. Epub 2013 Dec 13. PubMed PMID: 24266758; PubMed Central PMCID: PMC3980028. 

Sanchez V, Moore CF, Brunzell DH, Lynch WJ. Effect of wheel-running during abstinence on subsequent nicotine-seeking in rats. Psychopharmacology (Berl). 2013 Jun; 227(3):403-11. doi: 10.1007/s00213-012-2964-x. Epub 2013 Jan 31. PubMed PMID: 23371488; PubMed Central PMCID: PMC3656970.